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Metronidazole is one of the rare examples of a drug developed against a parasite which has since gained broad use as an antibacterial agent. Metronidazole should be used with caution in patients with active or chronic severe peripheral and central nervous system diseases due to the risk of neurological aggravation. Metronidazole should be used with caution in patients with active or chronic severe peripheral and central nervous system diseases due to the risk of neurological aggravation. Metronidazole antibiotic is marketed by Pfizer under the trade name Flagyl, and also by various generic manufacturers, who sell it at a cheaper price. The formulary at most hospitals for prophylaxis against anaerobic infection after bowel surgery, and for treatment of wound abscess. Minor side effects are appetite loss, drowsiness, diarrhea, metallic taste, headaches, stomach upset and vomiting. Metronidazole should be used with caution in patients with active or chronic severe peripheral and central nervous system diseases due to the risk of neurological aggravation.
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