Interation of metformin and spironolactone:
It is recommended that people taking this medicine have their fluid and salt balance monitored regularly. Aldactone is also used in combination with other medicines to treat precocious puberty or myasthenia gravis. Spironolactone therefore increases the amount of salts such as sodium that they filter out of the blood by the kidneys, where it is involved in controlling the balance of salt and water in the body.
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