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It reduces simply the symptoms and signs of arthritis. Celebrex is used to reduce pain and inflammation of arthritis, the most common adverse effects are headache, abdominal pain, and nausea versus prescription ibuprofen and naproxen. It is very important that you do not take additional medications containing aspirin if you are allergic to Celecoxib, aspirin or other NSAIDs may experience an allergic reaction to Celecoxib and should not take Celecoxib. Celecoxib is used to treat acute pain or menstrual pain and discomfort.